Assessment and management of blood-pressure variability

Posted at — Mario Hernández Cueto — marzo 15th, 2013 — 10:08 under comentario

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Assessment and management of blood-pressure variability

ComentandoPor: Gianfranco Parati, Juan E. Ochoa, Carolina Lombardi y Grzegorz Bilo.  Nature Reviews Cardiology 10, 143-155 (March 2013).

Blood pressure (BP) is characterized by marked short-term fluctuations occurring within a 24 h period (beat-to-beat, minute-to-minute, hour-to-hour, and day-to-night changes) and also by long-term fluctuations occurring over more-prolonged periods of time (days, weeks, months, seasons, and even years). Rather than representing ‘background noise’ or a randomly occurring phenomenon, these variations have been shown to be the result of complex interactions between extrinsic environmental and behavioural factors and intrinsic cardiovascular regulatory mechanisms. Although the adverse cardiovascular consequences of hypertension largely depend on absolute BP values, evidence from observational studies and post-hoc analyses of data from clinical trials have indicated that these outcomes might also depend on increased BP variability (BPV).   [Actualizado: 15 de marzo de 2013]

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