The effects of dietary patterns on plasma renin activity: results from the Dietary Approaches to Stop Hypertension trial

Posted at — Mario Hernández Cueto — noviembre 5th, 2012 — 9:49 under investigaciones

The effects of dietary patterns on plasma renin activity: results from the Dietary Approaches to Stop Hypertension trial

InvestigacionesPor:  Q Chen1, S Turban, E R Miller y L J Appel.   Journal of Human Hypertension (2012) 26, 664–669.


A diet rich in fruits, vegetables and low-fat dairy products, and reduced in saturated fat, total fat and cholesterol (the ‘DASH’ diet) significantly lowers blood pressure (BP). Previous studies have documented that certain therapies that lower BP increase plasma renin activity (PRA). Using data from the Dietary Approaches to Stop Hypertension (DASH) trial, we assessed the effects of dietary patterns on PRA and determined the relationship of change in PRA with change in BP on each diet. After eating a control diet for 3 weeks, participants were then randomized to receive for 8 weeks: the control diet, a diet rich in fruits and vegetables (F/V), or the DASH diet. Baseline and follow-up levels of PRA were available in 381 participants.  (publicado: 05–11-2012)

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