Prediction of Weight Loss and Regain Following Dietary, Lifestyle, and Pharmacologic Intervention

Posted at — Mario Hernández Cueto — junio 13th, 2012 — 7:11 under factores de riesgo

Prediction of Weight Loss and Regain Following Dietary, Lifestyle, and Pharmacologic Intervention

2-riesgo-cardiovascularPor: A Napolitano, S R Miller, P R Murgatroyd, B Delafont, A Brooke, M Elkhawad, C Y Tan, S Virtue, A Vidal-Puig y D J Nunez. Clinical Pharmacology & Therapeutics (2012); 91 6, 1027–1034.

To develop statistical models for predicting weight loss and regain, we analyzed the phenotypic responses in an outpatient study of 60 obese subjects randomized to one of three 12-week interventions, diet (–600 kcal) alone, diet with exercise, and diet with sibutramine. This was followed by 12 weeks of observation.

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