Diabetes mellitus

15 abril 2014

La forma en que se digieren los carbohidratos podría influir sobre el aumento de peso, según un estudio

Filed under: Noticias — Arturo Hernández Yero @ 16:54

La forma en que el organismo digiere los carbohidratos podría influir en el riesgo de obesidad, indica un nuevo estudio genético.

Los investigadores se enfocaron en un gen llamado AMY1, responsable de una enzima de la saliva conocida como amilasa salival. Cuando la comida entra en la boca, la enzima inicia el proceso de absorción del almidón que continúa en el sistema digestivo. Los almidones son un tipo de carbohidrato.

Las personas típicamente tienen dos copias del AMY1, pero el número de copias puede variar mucho. Se cree que los números más altos del gen evolucionaron en respuesta a dietas que contenían unos niveles más altos de almidón, apuntaron los investigadores.

Estudiaron el número de copias del AMY1 en miles de personas de Francia, Singapur, Suecia y Reino Unido, y hallaron que las que tenían un número bajo de copias eran más propensas a ser obesas.

Las personas con menos de cuatro copias del gen tenían unas ocho veces más probabilidades de ser obesas que las que tenían nueve copias. Por cada copia adicional del gen, una persona tenía alrededor de un 20 por ciento menos de probabilidades de ser obesa, según los autores del estudio, publicado en la edición del 30 de marzo de la revista Nature Genetics.

“Creo que es un descubrimiento importante porque sugiere que la forma en que digerimos el almidón y cómo los productos finales de la digestión de los carbohidratos complejos se comportan en el intestino podrían ser factores importantes en el riesgo de obesidad”, apuntó en un comunicado de prensa del Colegio Imperial de Londres el autor colíder del estudio, el Dr. Philippe Froguel, catedrático de medicina genómica de la Facultad de Salud Pública del colegio.

“Se necesita más investigación para comprender si alterar la digestión de los alimentos almidonados podría mejorar o no la capacidad de alguien para perder peso, o evitar que una persona se haga obesa”, planteó Froguel.

“También nos interesa si hay un vínculo entre esta variación genética y el riesgo de otros trastornos metabólicos de las personas, como la diabetes, ya que las personas con un número bajo de copias del gen de la amilasa salival también podrían ser intolerantes a la glucosa”, comentó Froguel.

Estudios anteriores que investigaban la obesidad han identificado variaciones en los genes que actúan en el cerebro, y que con frecuencia resultan en diferencias en el apetito, apuntó en el comunicado de prensa el primer autor del estudio, el Dr. Mario Falchi, también del Colegio Imperial de Londres. “Nuestro hallazgo se relaciona con la forma en que el cuerpo maneja físicamente la digestión de los carbohidratos”.

Falchi dijo que los investigadores comienzan a obtener una imagen más clara de una combinación de factores genéticos que contribuyen a las probabilidades de una persona de volverse obesa. “Esto debe en última instancia ayudarnos a hallar mejores formas de afrontar la obesidad”, planteó.

JUEVES, 3 de abril de 2014 (HealthDay News) —

Artículo por HealthDay, traducido por Hispanicare

FUENTE: Imperial College London, news release, March 30, 2014

HealthDay

http://www.nlm.nih.gov/medlineplus/spanish/news/fullstory_145524.html

Perspectiva clínica de los trastornos de la glucemia en pacientes hospitalizados

Filed under: Artículos cubanos — Arturo Hernández Yero @ 16:50

Clinical perspective of glycemic disorders in hospitalized patients

Dr. Emilio Fidel Buchaca Faxas, Dr. Francisco Fernández Valdés, Dra. Lays Rodríguez Amador, Dr. Sergio Bermúdez Rojas

Hospital Clinicoquirúrgico “Hermanos Ameijeiras”. La Habana, Cuba.

La Declaración de Melbourne sobre diabetes

Filed under: Temas interesantes — Arturo Hernández Yero @ 16:46

Durante el Congreso Mundial de Diabetes 2013, celebrado en Melbourne(Australia), parlamentarios invitados en representación de 50 países han acordado y firmado una declaración sobre diabetes. La Declaración de Melbourne sobre diabetes se aprobó el día 2 de diciembre de 2013. La Declaración hace un llamado para que se actúe con urgencia a fin de resolver la pandemia de diabetes y nuestros dedicados signatarios se comprometen a trabajar desde todos los parlamentos a fin de ayudar a prevenir la incidencia de diabetes, garantizar el diagnóstico precoz y mejorar el tratamiento de las personas con la afección.

Texto completo de la Declaración de Melbourne

PARLIAMENTARY CHAMPIONS FOR DIABETES FORUM

Parliament House, Spring Street Melbourne

Co-Chairs Sir Michael Hirst & Guy Barnett

MELBOURNE DECLARATION ON DIABETES Introduction We Members of Parliament from around the world with a special interest in supporting people with diabetes, their families and those at risk of diabetes are gathered here in Melbourne for the first global Parliamentary Champions For Diabetes forum just prior to the World Diabetes Congress, 2 – 6 December 2013. We are concerned by the increasingly serious health, economic and social threat faced by nations large and small, rich and poor and their people of whatever gender, age, colour, creed or social class by the diabetes pandemic. The global challenge

There are an estimated 382 million people with diabetes in the world and that number is expected to rise to 592 million by 2035. 80% of people with diabetes live in low and middle-income countries. Diabetes will cause 5.1 million deaths in 2013 – one person every six seconds.

All types of diabetes are increasing – type 1 diabetes, type 2 diabetes and gestational diabetes. Younger and younger people are developing diabetes. An estimated 46% of type 2 diabetes is undiagnosed. 21 million live births will be affected by diabetes in 2013 and the latest evidence of epigenetic and “intergenerational” diabetes is alarming. A further 316 million people currently have impaired glucose tolerance and are at high risk of developing type 2 diabetes and this is set to increase to 471 million by 2035. Diabetes is a major threat to the health and productivity of all nations. Diabetes is a leading cause of blindness, amputations, kidney failure, heart attacks and stroke, and early death. Disadvantaged

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Parliamentary Champions For Diabetes Forum – Melbourne Declaration on Diabetes

people in every country carry the greatest burden and indigenous communities are especially vulnerable. The economic burden of diabetes is immense and in 2013 diabetes will take up 11% of worldwide health expenditure – USD 548 billion dollars. However, there are solutions for managing and preventing the diabetes pandemic. Affordable access to healthcare providers and treatments including insulin, other oral and injectable medicines, self-management supports and technologies can help prevent most of the complications of diabetes. The response of the international community The 66th World Health Assembly (WHA) held in May 2013 has adopted 9 global targets and 25 indicators to help address the non-communicable diseases (NCDs) pandemic. Diabetes is the only one of the four major NCDs with its own global target – halt the rise in diabetes and obesity by 2025. Diabetes is not just a health issue, it is a development issue and requires concerted policy action across many sectors. The International Diabetes Federation (IDF) is the unique global voice for people with diabetes and those at risk. Its Member Associations in nearly every country of the world are likewise advocates for people with diabetes and those at risk. We acknowledge their support for us and our objectives. IDF plays a pivotal role in efforts to reduce the global impact of diabetes, catalysing grass roots activism, influencing global health and development policy, and driving the global agenda on diabetes. Twenty years after the World Diabetes Congress in Japan, the Western Pacific region is again in the global health spotlight with Melbourne hosting the World Diabetes Congress from 2 to 6 December 2013. In Australia, 8% of the population is living with diabetes and this is predicted to

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Parliamentary Champions For Diabetes Forum – Melbourne Declaration on Diabetes

increase to 14% in the next twenty years. Indigenous communities in Australia are three or four times more likely to have diabetes and the rate of complications is also much higher, like it is in many other indigenous communities throughout the world. The contribution of Parliamentarians

There are some existing parliamentary diabetes support groups in various countries throughout the world, including Australia. However, there are currently no formal links between these groups. Nor is there a dedicated effort to both sustain and build these groups.

The first Parliamentary Champions For Diabetes forum being held in Melbourne from 30 November 2013 to 2 December 2013 has created the opportunity to establish a global network of parliamentarians for diabetes. Parliamentary champions for diabetes, the IDF and IDF Member Associations and others, can from their different perspectives, influence governments, key decision-makers and others to take action to support diabetes prevention, management plans and strategies. Parliamentarians can also have significant influence in their community and elsewhere. This declaration offers a means to expedite these desirable objectives. Every nation needs a national strategy and action plan to prevent and manage the diabetes pandemic and an effective global Parliamentarians for Diabetes global network can help facilitate this objective.

Accordingly, we believe that urgent action is required by individuals, families, communities, health care services, industry, governments and international organisations to ensure prevention, and then early diagnosis, management and access to adequate care, treatment and medicines for all those living with diabetes. We commit ourselves to working across Parliaments with all who have a special interest in diabetes and hereby agree to establish a ‘Parliamentarians for Diabetes’ global network with the following objectives to:

1. Exchange policy views and practical initiatives of relevance and to hear from experts on

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Parliamentary Champions For Diabetes Forum – Melbourne Declaration on Diabetes

opportunities for action and progress in the prevention and management of diabetes. To always strive for ‘best practice’, and advocate for people with diabetes, their families and carers, and those at risk and to become a powerful force internationally to respond in a coordinated and focussed way to the diabetes pandemic and to promote the diabetes cause.

2. Provide parliamentarians with the opportunity to attend meetings organised by the IDF and their Member Associations, aiming to improve health outcomes for people with diabetes, stop discrimination towards people with diabetes and prevent development of type 2 diabetes. A special focus should be the different regions of the globe to ensure practical solutions are offered.

3. Establish a platform for the dialogue between IDF Member Associations and other stakeholders to exchange information and discuss special areas of common interest. These will include prevention, workforce, costs of diabetes, access to medicines, and effective strategies to combat and manage the pandemic. To report back to ministers, parliamentarians and other key decision-makers in our home countries and to seek commitments to deliver on the targets set at the 66th WHA in 2013. The global network will support the sharing of resources such as research, legislative initiatives, prevention campaigns and joint initiatives relevant to the various regions of the globe.

4. Encourage all governments to acknowledge that diabetes is a national health priority that requires a comprehensive action plan leading to action.

5. Respond to and participate in relevant debate and discussion on and related to the World Health Assembly, World Health Organisation, United Nations and other appropriate organisations or government bodies and specifically to ensure the inclusion of diabetes and NCDs in the post-2015 development framework noting this framework should be aligned with the goals and targets on diabetes agreed at the 66th WHA. Diabetes intersects all major dimensions of global development, including poverty reduction, gender inequality, education, environmental sustainability and infectious diseases.

6. Confer honour and express gratitude to those Members of Parliament supporting the

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Parliamentary Champions For Diabetes Forum – Melbourne Declaration on Diabetes

diabetes cause, wherever they may be and to use our best endeavours to recruit other Members of Parliament for this purpose.

7. Create opportunities for networking and building relationships between Members of Parliament, other key decision-makers, the IDF and its Member Associations and others. To hold meetings in various regions of the globe as agreed, and to meet again as a Global Forum at the next World Diabetes Congress in 2015.

8. Appoint a global co-ordinator with appropriate administrative and management support to assist the global network to achieve the above objectives.

Carried unanimously this 2nd day of December 2013.

Autor: Arturo Hernández Yero | Contáctenos
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