Nefrologia

3 agosto 2011

Rituximab Targets Podocytes in Recurrent Focal Segmental Glomerulosclerosis

Filed under: Artículos interesantes — Mario Hernández Cueto @ 10:42

Rituximab Targets Podocytes in Recurrent Focal Segmental Glomerulosclerosis

Por: Alessia Fornoni, Junichiro Sageshima, Changli Wei, Sandra Merscher-Gomez, Robier Aguillon-Prada, Alexandra N. Jauregui, et al.  Science Translational Medicine June 2011,3:(85): 85ra46

Focal segmental glomerulosclerosis (FSGS) is a glomerular disease characterized by proteinuria, progression to end-stage renal disease, and recurrence of proteinuria after kidney transplantation in about one-third of patients. It has been suggested that rituximab might treat recurrent FSGS through an unknown mechanism

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