Instituto de Hematología e Inmunología

10 junio 2016

Blood Journal, último número, tabla de contenido aqui

Filed under: Novedades — ihi @ 11:18

Table of Contents

 

June 09, 2016; 127 (23)
Blood Flashback

Solomon A, Fahey JL, Malmgren RA. Immunohistologic localization of gamma-1-macroglobulins, beta-2A-myeloma proteins, 6.6 S gamma-myeloma proteins and Bence Jones proteins. Blood. 1963;21(4):403-423.

Inside Blood Commentaries

Platelets and Thrombopoiesis
Platelet disorders: the next generation is in
A. Koneti Rao and Natthapol Songdej
Hematopoiesis and Stem Cells
The identity crisis of Hif-1α in HSC biology
Stephen M. Sykes
Lymphoid Neoplasia
BRAF inhibitor: targeted therapy in hairy cell leukemia
Michael R. Grever
Lymphoid Neoplasia
Novel NF-κB regulator in ABC DLBCL
Georg Lenz
Myeloid Neoplasia
Enhancing cytotoxicity of immunotoxins in AML
Naval Daver and Farhad Ravandi
Clinical Trials and Observations
VWF, ADAMTS13, and acute coronary syndromes
Neal S. Kleiman

Plenary Paper

Thrombosis and Hemostasis
A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders
Ilenia Simeoni, Jonathan C. Stephens, Fengyuan Hu, Sri V. V. Deevi, Karyn Megy, Tadbir K. Bariana, Claire Lentaigne, Sol Schulman, Suthesh Sivapalaratnam, Minka J. A. Vries, Sarah K. Westbury, Daniel Greene, Sofia Papadia, Marie-Christine Alessi, Antony P. Attwood, Matthias Ballmaier, Gareth Baynam, Emilse Bermejo, Marta Bertoli, Paul F. Bray, Loredana Bury, Marco Cattaneo, Peter Collins, Louise C. Daugherty, Rémi Favier, Deborah L. French, Bruce Furie, Michael Gattens, Manuela Germeshausen, Cedric Ghevaert, Anne C. Goodeve, Jose A. Guerrero, Daniel J. Hampshire, Daniel P. Hart, Johan W. M. Heemskerk, Yvonne M. C. Henskens, Marian Hill, Nancy Hogg, Jennifer D. Jolley, Walter H. Kahr, Anne M. Kelly, Ron Kerr, Myrto Kostadima, Shinji Kunishima, Michele P. Lambert, Ri Liesner, José A. López, Rutendo P. Mapeta, Mary Mathias, Carolyn M. Millar, Amit Nathwani, Marguerite Neerman-Arbez, Alan T. Nurden, Paquita Nurden, Maha Othman, Kathelijne Peerlinck, David J. Perry, Pawan Poudel, Pieter Reitsma, Matthew T. Rondina, Peter A. Smethurst, William Stevenson, Artur Szkotak, Salih Tuna, Christel van Geet, Deborah Whitehorn, David A. Wilcox, Bin Zhang, Shoshana Revel-Vilk, Paolo Gresele, Daniel B. Bellissimo, Christopher J. Penkett, Michael A. Laffan, Andrew D. Mumford, Augusto Rendon, Keith Gomez, Kathleen Freson, Willem H. Ouwehand, and Ernest Turro

Perspectives

Is watch and wait still acceptable for patients with low-grade follicular lymphoma?
James O. Armitage and Dan L. Longo

Blood Spotlight

Hepcidin in the diagnosis of iron disorders
Domenico Girelli, Elizabeta Nemeth, and Dorine W. Swinkels

Review Article

Inherited platelet disorders: toward DNA-based diagnosis
Claire Lentaigne, Kathleen Freson, Michael A. Laffan, Ernest Turro, and Willem H. Ouwehand

How I Treat

How I vaccinate blood and marrow transplant recipients
Paul A. Carpenter and Janet A. Englund

Clinical Trials And observations

Randomized phase 2 study: elotuzumab plus bortezomib/dexamethasone vs bortezomib/dexamethasone for relapsed/refractory MM
Andrzej Jakubowiak, Massimo Offidani, Brigitte Pégourie, Javier De La Rubia, Laurent Garderet, Kamel Laribi, Alberto Bosi, Roberto Marasca, Jacob Laubach, Ann Mohrbacher, Angelo Michele Carella, Anil K. Singhal, L. Claire Tsao, Mark Lynch, Eric Bleickardt, Ying-Ming Jou, Michael Robbins, and Antonio Palumbo

Hematopoiesis And stem Cells

Brief Report
Adult hematopoietic stem cells lacking Hif-1α self-renew normally
Milica Vukovic, Catarina Sepulveda, Chithra Subramani, Amélie V. Guitart, Jasmine Mohr, Lewis Allen, Theano I. Panagopoulou, Jasmin Paris, Hannah Lawson, Arnaud Villacreces, Alejandro Armesilla-Diaz, Deniz Gezer, Tessa L. Holyoake, Peter J. Ratcliffe, and Kamil R. Kranc

Immunobiology

e-Blood
Manipulating leukocyte interactions in vivo through optogenetic chemokine release
Milka Sarris, Romain Olekhnovitch, and Philippe Bousso

Lymphoid Neoplasia

BRAF inhibition in hairy cell leukemia with low-dose vemurafenib
Sascha Dietrich, Andreas Pircher, Volker Endris, Frédéric Peyrade, Clemens-Martin Wendtner, George A. Follows, Jennifer Hüllein, Alexander Jethwa, Elena Ellert, Tatjana Walther, Xiyang Liu, Martin J. S. Dyer, Thomas Elter, Tilman Brummer, Robert Zeiser, Michael Hermann, Michael Herold, Wilko Weichert, Claire Dearden, Torsten Haferlach, Martina Seiffert, Michael Hallek, Christof von Kalle, Anthony D. Ho, Anita Gaehler, Mindaugas Andrulis, Michael Steurer, and Thorsten Zenz
miR-181a negatively regulates NF-κB signaling and affects activated B-cell–like diffuse large B-cell lymphoma pathogenesis
Goldi A. Kozloski, Xiaoyu Jiang, Shruti Bhatt, Jose Ruiz, Francisco Vega, Rita Shaknovich, Ari Melnick, and Izidore S. Lossos

Myeloid Neoplasia

All-trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD+ leukemia stem cells in vitro and in vivo
Hayley S. Ma, Sarah M. Greenblatt, Courtney M. Shirley, Amy S. Duffield, J. Kyle Bruner, Li Li, Bao Nguyen, Eric Jung, Peter D. Aplan, Gabriel Ghiaur, Richard J. Jones, and Donald Small
Decitabine enhances anti-CD33 monoclonal antibody BI 836858–mediated natural killer ADCC against AML blasts
Sumithira Vasu, Shun He, Carolyn Cheney, Bhavani Gopalakrishnan, Rajeswaran Mani, Gerard Lozanski, Xiaokui Mo, Veronica Groh, Susan P. Whitman, Renate Konopitzky, Christian Kössl, Donna Bucci, David M. Lucas, Jianhua Yu, Michael A. Caligiuri, William Blum, Paul J. Adam, Eric Borges, Bjoern Rueter, Karl-Heinz Heider, Guido Marcucci, and Natarajan Muthusamy
Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6
Iris Z. Uras, Gina J. Walter, Ruth Scheicher, Florian Bellutti, Michaela Prchal-Murphy, Anca S. Tigan, Peter Valent, Florian H. Heidel, Stefan Kubicek, Claudia Scholl, Stefan Fröhling, and Veronika Sexl

Platelets And thrombopoiesis

A gain-of-function variant in DIAPH1 causes dominant macrothrombocytopenia and hearing loss
Simon Stritt, Paquita Nurden, Ernest Turro, Daniel Greene, Sjoert B. Jansen, Sarah K. Westbury, Romina Petersen, William J. Astle, Sandrine Marlin, Tadbir K. Bariana, Myrto Kostadima, Claire Lentaigne, Stephanie Maiwald, Sofia Papadia, Anne M. Kelly, Jonathan C. Stephens, Christopher J. Penkett, Sofie Ashford, Salih Tuna, Steve Austin, Tamam Bakchoul, Peter Collins, Rémi Favier, Michele P. Lambert, Mary Mathias, Carolyn M. Millar, Rutendo Mapeta, David J. Perry, Sol Schulman, Ilenia Simeoni, Chantal Thys, BRIDGE-BPD Consortium, Keith Gomez, Wendy N. Erber, Kathleen Stirrups, Augusto Rendon, John R. Bradley, Chris van Geet, F. Lucy Raymond, Michael A. Laffan, Alan T. Nurden, Bernhard Nieswandt, Sylvia Richardson, Kathleen Freson, Willem H. Ouwehand, and Andrew D. Mumford

Thrombosis And hemostasis

A novel DFP tripeptide motif interacts with the coagulation factor XI apple 2 domain
Szu S. Wong, Søren Østergaard, Gareth Hall, Chan Li, Philip M. Williams, Henning Stennicke, and Jonas Emsley
Whole-exome sequencing to identify genetic risk variants underlying inhibitor development in severe hemophilia A patients
Marcin M. Gorski, Kevin Blighe, Luca A. Lotta, Emanuela Pappalardo, Isabella Garagiola, Ilaria Mancini, Maria Elisa Mancuso, Maria Rosaria Fasulo, Elena Santagostino, and Flora Peyvandi

Letters To Blood

Acquired intracoronary ADAMTS13 deficiency and VWF retention at sites of critical coronary stenosis in patients with STEMI
Giovanni Pedrazzini, Luigi Biasco, Irmela Sulzer, Adriana Anesini, Tiziano Moccetti, Johanna A. Kremer Hovinga, and Lorenzo Alberio
First report of MYD88 L265P somatic mutation in IgM-associated light-chain amyloidosis
Rajshekhar Chakraborty, Anne J. Novak, Stephen M. Ansell, Eli Muchtar, Prashant Kapoor, Suzanne R. Hayman, Angela Dispenzieri, Francis K. Buadi, Martha Q. Lacy, Rebecca L. King, and Morie A. Gertz

Blood Work

Intravascular large B-cell lymphoma in a kidney biopsy
Francisco Diaz-Crespo and Manuela Mollejo
Primary effusion lymphoma and concurrent progressive Kaposi sarcoma associated with elevated interleukin-6
Drew Pratt and Thomas S. Uldrick

Issue Highlights

Adult hematopoietic stem cells lacking Hif-1α self-renew normally
BRAF inhibition in hairy cell leukemia with low-dose vemurafenib
A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders
Is watch and wait still acceptable for patients with low-grade follicular lymphoma?
Hepcidin in the diagnosis of iron disorders
Whole-exome sequencing to identify genetic risk variants underlying inhibitor development in severe hemophilia A patients
A gain-of-function variant in DIAPH1 causes dominant macrothrombocytopenia and hearing loss

Leading the way in experimental and clinical research in hematology

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