Tag Archive 'sexo'

Lunes 8 / abril / 2013

Relationship Between Uric Acid and Vascular Structure and Function in Hypertensive Patients and Sex-Related Differences

Filed under: Editorial — Mario Hernández Cueto — abril 8th, 2013 — 8:25

Editorial. Los trabajos y opiniones que aquí se exponen son orientadores de lo que se publica en Cuba y en el mundo sobre aspectos relevantes de la hipertensión arterial.


Relationship Between Uric Acid and Vascular Structure and Function in Hypertensive Patients and Sex-Related Differences

EditorialPor: Manuel A. Gómez-Marcos, Jose I. Recio-Rodríguez, María C. Patino-Alonso, Cristina Agudo-Conde, Emiliano Rodríguez-Sánchez, Leticia Gómez-Sánchez, Marta Gómez-Sánchez y Luis García-Ortiz.  American Journal of Hypertension, Volume 26, Issue 5, Pp. 599-607.

We sought to analyze the relationship between uric acid (UA) and vascular structure and function based on the carotid intima-media thickness, the pulse-wave velocity (PWV), the central arterial pressure, and the augmentation index in hypertensive patients and to evaluate the sex-related differences.
A cross-sectional study was performed with 366 hypertensive individuals aged 34–75years (men = 61.74%). The vascular structure was assessed based on the carotid intima-media thickness, the arterial stiffness was assessed by PWV, and the vascular function was assessed using hemodynamic parameters such as the central and peripheral augmentation index and the ambulatory arterial stiffness index (AASI).
Serum UA showed a positive correlation with the mean maximum intima-media thickness and PWV, and this parameter showed a negative correlation with the central and peripheral augmentation indices, although this relationship was lost after adjusting for confounding factors. AASI showed a positive association in women and a negative association in men after adjusting for confounding factors. [Actualizado: 8 de abril de 2013]

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Viernes 15 / febrero / 2013

Blood pressure change and antihypertensive treatment in old and very old people: evidence of age, sex and cohort effects

Filed under: Editorial — Mario Hernández Cueto — febrero 15th, 2013 — 8:16

A manera de editorial. Los trabajos y opiniones que aquí se exponen son orientadores de lo que se publica en Cuba y en el mundo sobre aspectos relevantes de la hipertensión arterial.

Blood pressure change and antihypertensive treatment in old and very old people: evidence of age, sex and cohort effects

EditorialPor: L Molander y H Lövheim.  Journal of Human Hypertension (2013) 27, 197–203.

The epidemiology of blood pressure in very old age has not been thoroughly studied. The objective of this study was to study blood pressure changes throughout old age and changes in blood pressure and antihypertensive drug use from 1981 to 2005. The study includes 1133 blood pressure measurements from two studies carried out in Umeå, Sweden. The U70 study (1981–1990) included individuals aged 70–88 and the Umeå 85+/GERDA study (2000–2005) covered people aged 85, 90 or greater than or equal to 95 years. In these analyses of two population-based studies of old and very old people spanning the years 1981 to 2005, decreasing mean blood pressure was found for higher age in both cross-sectional and longitudinal analyses. [Actualizado: 15 febrero de 2013]

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Martes 6 / marzo / 2012

Sex-related differences in pharmacokinetics and pharmacodynamics of anti-hypertensive drugs

Filed under: factores de riesgo — Mario Hernández Cueto — marzo 6th, 2012 — 9:02

Sex-related differences in pharmacokinetics and pharmacodynamics of anti-hypertensive drugs

2-riesgo-cardiovascularPor: Koichi Ueno y Hiromi Sato.  Hypertension Research (2012) 35, 245–250.

Clear evidence for sex-specific differences in the pharmacokinetic or pharmacodynamic properties of anti-hypertension drugs has accumulated. The population most frequently in need of clinical treatment for hypertension or heart failure is, of course, the elderly. They often take many kinds of medications, so whole-body pharmacokinetics and pharmacodynamics must always be taken into consideration during treatment planning.

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