Impact of one or two visits strategy on hypertension burden estimation in HYDY, a population-based cross-sectional study: implications for healthcare resource allocation decision making

Por: Pietro Amedeo Modesti, Stefano Rapi, Mohamed Bamoshmoosh, Marzia Baldereschi, Luciano Massetti, Luigi Padeletti, Gian Franco Gensini, Dong Zhao, Dawood Al-Hidabi, Husni Al Goshae.  BMJ Open 2012;2:e001062 doi:10.1136/bmjopen.

Hypertension prevalence (age-standardised to the WHO world population 2001) based on fulfilling the same criteria on both visits (11.3%; 95% Cl 10.7% to 11.9%), was 35% lower than estimation based on the first visit (17.3%; 16.5% to 18.0%). Advanced age, blood glucose ≥7 mmol/l or proteinuria ≥1+ at dipstick test at visit one were significant predictors of confirmation at visit 2. The 959 participants found to be hypertensive at visit 1 or at visit 2 only and thus excluded from the final diagnosis had a rate of proteinuria (5.0%; 3.8% to 6.5%) comparable to rates of the general population (6.1%; 5.6% to 6.6%), and of subjects normotensive at both visits (5.6%; 5.1% to 6.2%). Only 1.9% of Yemen population classified at high or very high cardiovascular (CV) risk at visit 1 moved to average, low or moderate CV risk categories after two visits.
Hypertension prevalence based on readings obtained after two visits is 35% lower than estimation based on the first visit, subjects were excluded from final diagnosis belonging to low CV risk classes. [Actualizado: 02 de mayo 2013].

Tags: carga, Estudio HYDY, Revisión

Combined effect of angiotensin II receptor blocker and either a calcium channel blocker or diuretic on day-by-day variability of home blood pressure: the Japan Combined Treatment With Olmesartan and a Calcium-Channel Blocker Versus Olmesartan and Diuretics Randomized Efficacy Study.

Por: Matsui Y, O’Rourke MF, Hoshide S, Ishikawa J, Shimada K y Kario K. Hypertension, 2012 Jun. Vol. 59, Issue: 6: 1132-8. Cochrane BVS.

Day-by-day home blood pressure (BP) variability (BPV) was reported to be associated with increased cardiovascular risk. We aimed to test the hypothesis that the angiotensin II receptor blocker/calcium-channel blocker combination decreases day-by-day BPV more than the angiotensin II receptor blocker/diuretic combination does and investigated the mechanism underlying the former reduction. [publicada: 21 de diciembre 2012]

Tags: eficacia, Estudio, medicamentos, Revisión

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and
triglyceride (Review)

Por:  Graudal Niels Albert, Hubeck-Graudal Thorbjorn y Jurgens Gesche. Cochrane Database of Systematic Reviews.  The Cochrane Library,  2011,  Issue 11, Art. No. CD004022.

In spite of more than 100 years of investigations the question of reduced sodium intake as a health prophylaxis initiative is still unsolved. To estimate the effects of low sodium versus high sodium intake on systolic and diastolic blood pressure (SBP and DBP), plasma or serum levels of renin, aldosterone, catecholamines, cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL) and triglycerides. [publicada: 11 de diciembre 2012].

Tags: actividad de la renina, aldosterona, colesterol, consumo, Revisión, sal, trigliceridos

Cumplimiento farmacológico en el tratamiento de la hipertensión arterial. Revisión de los estudios publicados entre los años 1975 y 2011

Por: Espinosa García, J.; Martell Claros, N.; Llerena Ruiz, A y Fernández Bergés Gurrea, D.  Semergen. 2012;38:292-300.- vol.38 núm 05.

Revisión sistemática de artículos publicados sobre cumplimiento, desde 1975 al 1 de junio de 2011, y más específicamente los que miden el cumplimiento farmacológico en la hipertensión arterial (HTA) utilizando métodos de medida indirectos (recuento de comprimidos y/o monitores electrónicos de control de la medicación [MEMS]). Los descriptores usados fueron: hypertension AND patient compliance AND medication adherence.  El principal objetivo es actualizar el tema del cumplimiento terapéutico en HTA en todo el mundo, con especial atención a España, así como realizar una evaluación crítica de la evolución del cumplimiento terapéutico en el periodo 1975-2011.
Después de analizar 37 estudios de investigación internacionales publicados, los resultados fueron: número total de pacientes hipertensos de 8.623, un 25,62% incumplidores (n=2.209; IC 95% 23,82-27,42) y un 74,38% cumplidores (n=6.414; IC 95% 73,32-75,44) y la media ponderada del porcentaje de incumplimiento fue del 37,60%.
Se concluye que el porcentaje de incumplimiento en el tratamiento farmacológico de la HTA en todo el mundo es elevado. [publicada el 27 de noviembre de 2012]

Tags: 1975 a 2011, cumplimiento terapétutico, Revisión