Plasma Total Testosterone and Incident Cardiovascular Events in Hypertensive Patients

Por: Charalambos Vlachopoulos, Nikolaos Ioakeimidis,  Dimitrios Terentes-Printzios, Konstantinos Aznaouridis, Konstantinos Rokkas, Athanassios Aggelis, Alexandros Synodinos, George Lazaros y Christodoulos Stefanadis.  American Journal of Hypertension, volume 26, Issue 3, pp. 373-381.

Androgen deficiency confers an independent risk for cardiovascular events and total mortality. Hypertension, a major contributory factor to the development of cardiovascular disease, has also been associated with increased prevalence of low testosterone. We investigated whether low androgen concentration predicts incident major adverse cardiovascular events (MACE) in middle-aged nondiabetic hypertensive patients without clinical atherosclerosis. Our results show that low plasma testosterone is associated with increased risk for a MACE in hypertensive patients. Low endogenous androgen concentration improves risk prediction when added to standard risk factors and may represent a valuable biomarker of prediction of cardiovascular disease risk in these patients. [Actualizado: 26 de febrero de 2013].

Tags: eventos cardiovasculares, Plasma total, testosterona

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The International Database of HOme blood pressure in relation to Cardiovascular Outcome (IDHOCO): moving from baseline characteristics to research perspectives

Por: Teemu J Niiranen, Lutgarde Thijs, Kei Asayama, Jouni K Johansson, Takayoshi Ohkubo, Masahiro Kikuya, José Boggia, Atsushi Hozawa, Edgardo Sandoya, George S Stergiou, Ichiro Tsuji, Antti M Jula, Yutaka Imai y Jan A Staessen on behalf of the IDHOCO investigators. Hypertension Research (2012) 35, 1072–1079.

The objective of this study is to construct an International Database of HOme blood pressure in relation to Cardiovascular Outcome (IDHOCO). The main goal of this database is to determine outcome-based diagnostic thresholds for the self-measured home blood pressure (BP). Secondary objectives include investigating the predictive value of white-coat and masked hypertension, morning and evening BP, BP and heart rate variability, and the home arterial stiffness index.  [publicado: 03 de diciembre de 2012]

Tags: eventos cardiovasculares

Association of Blood Pressure Control and Metabolic Syndrome With Cardiovascular Risk in Elderly
Japanese: JATOS Study. (en inglés)

Por: Yuhei Kawano, Toshio Ogihara, Takao Saruta, Yoshio Goto y Masao Ishii. American Journal of
Hypertension (2011); 24 11, 1250–1256.acto del síndrome metabólico (SM) sobre los eventos cardiovasculares en pacientes de edad avanzada no se ha aclarado. La hipótesis de que el impacto difiere entre pacientes con y sin riguroso control de la presión arterial (PA) y también entre las personas de edad temprana (<75 años) y tardía (≥ 75 años) de los pacientes de edad avanzada.

Tags: eventos cardiovasculares, pacientes ancianos, síndrome metabólico