Combination therapy of hypertension in the elderly: a subgroup analysis of the Combination of OLMesartan and a calcium channel blocker or diuretic in Japanese elderly hypertensive patients trial

Filed under: articulo original — enero 5th, 2015 — 11:39 — Mario Hernández Cueto

Combination therapy of hypertension in the elderly: a subgroup analysis of the Combination of OLMesartan and a calcium channel blocker or diuretic in Japanese elderly hypertensive patients trial

Revista Hypertension ResearchPor: Toshio Ogihara, Takao Saruta, Hiromi Rakugi, Ikuo Saito, Kazuaki Shimamoto, Hiroaki Matsuoka, Satoshi Teramukai, Jitsuo Higaki, Sadayoshi Ito y Kazuyuki Shimada for the COLM investigators.   Hypertension Research (2015) 38, 89–96.

Combination of OLMesartan and a calcium channel blocker or a diuretic in Japanese elderly hypertensive patients (COLM) trial demonstrated that olmesartan combinations with a CCB or diuretic have similar effects on reducing cardiovascular risk in elderly hypertensive patients. However, the safety profiles suggest that olmesartan combined with CCB may be preferable to olmesartan combined with diuretic. In this subgroup analysis, we further evaluated the effects and safety of these combinations in elderly (65–74 years old (y.o.)) and very elderly (75–84 y.o.) hypertensive patients.

Hypertension management initiative prospective cohort study: comparison between immediate and delayed intervention groups.

Filed under: articulo original — diciembre 22nd, 2014 — 7:36 — Mario Hernández Cueto

Hypertension management initiative prospective cohort study: comparison between immediate and delayed intervention groups.

revista-hypertension-research1Por: S W Tobe, M Moy Lum-Kwong, S Von Sychowski, K Kandukur, A Kiss y V Flintoft.  Journal of Human Hypertension (2014) 28, 44–50

The Heart and Stroke Foundation of Ontario’s Hypertension Management Initiative (HMI) was a pragmatic implementation of clinical practice guidelines for hypertension management in primary care clinics. The HMI was a prospective delayed phase cohort study of 11 sites enrolling patients in two blocks starting 9 months apart in 2007. The intervention was an evidence-informed chronic disease management program consisting of an interprofessional educational intervention with practice tools to implement the Canadian Hypertension Education Program’s clinical practice guidelines.

The influence of aging on the diagnosis of primary aldosteronism

Filed under: articulo original — diciembre 8th, 2014 — 14:07 — Mario Hernández Cueto

The influence of aging on the diagnosis of primary aldosteronism

Revista Hypertension ResearchPor: Chikako Nakama, Kei Kamide, Tatsuo Kawai, Kazuhiro Hongyo, Norihisa Ito, Miyuki Onishi, Yasushi Takeya, Koichi Yamamoto, Ken Sugimoto y Hiromi Rakug.   Hypertension Research (2014) 37, 1062–1067.

Primary aldosteronism (PA) is common in young or middle-aged hypertensive patients, but PA among the elderly has recently become more common. As salt sensitivity increases with age, plasma renin activity (PRA) tends to decrease, whereas the aldosterone-to-renin ratio (ARR) tends to increase in the elderly. The aim of this study was to clarify the influence of aging on the diagnosis of PA. We retrospectively evaluated 155 consecutively admitted patients who were not taking antihypertensive medications or calcium channel blockers and a blockers that underwent PRA and plasma aldosterone concentration (PAC) measurements.

Artículos Interesantes

Filed under: Artículos interesantes — diciembre 4th, 2014 — 11:47 — Mario Hernández Cueto

Revista: Journal of Human Hypertension

Can we identify response markers to antihypertensive drugs? First results from the IDEAL Trial

Por: F Gueyffier, F Subtil, T Bejan-Angoulvant, Y Zerbib, J P Baguet, J M Boivin10, A Mercier, G Leftheriotis1, J P Gagnol, J P Fauvel1, C Giraud, G Bricca, D Maucort-Boulch y  Erpeldinger for the IDEAL Trial Group.  Journal of Human Hypertension (2015) 29, 22–27.

The relation of potassium and sodium intakes to diet cost among US adults

Por: A Drewnowski, C D Rehm, M Maillot  y P Monsivais.  Journal of Human Hypertension (2015) 29, 14–21.

High–normal blood pressure is associated with new-onset electrocardiographic left ventricular hypertrophy

Por: H Ueda, M Miyawaki y H Hiraoka.   Journal of Human Hypertension (2015) 29, 9–13

Suitability of antiplatelet therapy in hypertensive patients.

Por: M J Martínez-Orozco, Z Perseguer-Torregrosa, V F Gil-Guillén, A Palazón-Bru, D Orozco-Beltran y C Carratalá-Munuera.  Journal of Human Hypertension (2015) 29, 40–45.

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