Archive for the 'factores de riesgo'

Lunes 9 / junio / 2014

Antihypertensive drug classes have different effects on short-term blood pressure variability in essential hypertension

Filed under: factores de riesgo — Mario Hernández Cueto — junio 9th, 2014 — 7:40

Antihypertensive drug classes have different effects on short-term blood pressure variability in essential hypertension

Riesgo cardiovascularPor: Natacha Levi-Marpillat, Isabelle Macquin-Mavier, Anne-Isabelle Tropeano, Gianfranco Parati y Patrick Maison.  Hypertension Research (2014) 37, 585–590.

Increased blood pressure variability (BPV) contributes to end-organ damage, cardiovascular events and mortality associated with hypertension. In a cohort of 2780 hypertensive patients treated by either calcium channel blockers (CCBs), diuretics, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs) or ß-blockers alone or in combination, we compared indices of short-term BPV according to the different treatments. Short-term BPV was calculated as the standard deviation (s.d.) of 24?h, daytime or nighttime systolic blood pressure and diastolic blood pressure (SBP and DBP).

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Martes 13 / mayo / 2014

Ácido úrico como factor de riesgo cardiovascular.

Filed under: factores de riesgo — Mario Hernández Cueto — mayo 13th, 2014 — 11:04

Ácido úrico como factor de riesgo cardiovascular.

Riesgo cardiovascularPor: J. Cebollada y J.A. Gimeno.  Hipertensiion y Riesgo Vascular, vol. 29. Núm. 02. abril 2012 -junio 2012.

La relación entre niveles séricos de ácido úrico y enfermedad cardiovascular es conocida desde hace tiempo. Sin embargo, ha sido en los últimos años cuando hemos encontrado creciente evidencia estableciendo el posible papel patogénico del ácido úrico en las diferentes manifestaciones de la enfermedad cardiovascular. La importancia de esta relación continúa siendo motivo de controversia y el debate sobre si debemos considerar la hiperuricemia un factor de riesgo vascular independiente o si es un mero epifenómeno de la enfermedad vascular o metabólica permanece abierto.

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Miércoles 9 / abril / 2014

Blood pressure variability and outcome after acute intracerebral haemorrhage: a post-hoc analysis of INTERACT2, a randomised controlled trial

Filed under: factores de riesgo — Mario Hernández Cueto — abril 9th, 2014 — 8:41

Blood pressure variability and outcome after acute intracerebral haemorrhage: a post-hoc analysis of INTERACT2, a randomised controlled trial

Riesgo cardiovascularPor: Lisa Manning MBChB , Yoichiro Hirakawa MD, Hisatomi Arima PhD,  Xia Wang MMed, Prof John Chalmers MD, Prof Jiguang Wang PhD, Prof Richard Lindley MD, Emma Heeley PhD, Candice Delcourt MD, Prof Bruce Neal MD, Prof Pablo Lavados MD, Prof Stephen M Davis MD, Prof Christophe Tzourio MD j k, Prof Yining Huang MD, Prof Christian Stapf MD, Prof Mark Woodward PhD, Prof Peter M Rothwell FMedSci, Prof Thompson G Robinson MD y  Prof Craig S Anderson MD.  The Lancet Neurology, Volume 13, Issue 4, Pages 364 – 373, April 2014

Stroke is a major cause of premature death and disability. The most serious and least treatable form—acute intracerebral haemorrhage—affects more than 1 million people each year worldwide.1 High blood pressure is a risk factor for stroke, particularly for both incident and recurrent intracerebral haemorrhage, but it also predicts a poor outcome when present in the first 24 h after the onset of intracerebral haemorrhage.2—4 Thus, early intensive control of blood pressure could be a safe and effective treatment for this disorder.5, 6 INTERACT2 showed improved functional outcomes with little risk for patients with intracerebral haemorrhage who received target-driven, early, intensive treatment to reduce blood pressure

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Martes 18 / marzo / 2014

Resistant hypertension: patient characteristics, risk factors, co-morbidities and outcomes

Filed under: factores de riesgo — Mario Hernández Cueto — marzo 18th, 2014 — 9:18

Resistant hypertension: patient characteristics, risk factors, co-morbidities and outcomes

Riesgo cardiovascularPor: A Oliveras y A de la Sierra.  Journal of Human Hypertension (2014) 28, 213–217.

Among the vast population of hypertensive subjects, between 10 and 15% do not achieve an adequate blood pressure (BP) control despite the use of at least three antihypertensive agents. This group, designated as having resistant hypertension (RH), represents one of the most important clinical challenges in hypertension evaluation and management. Resistant hypertensives are characterized by several clinical particularities, such as a longer history of hypertension, obesity and other accompanying factors, such as diabetes, left ventricular hypertrophy, albuminuria and renal dysfunction.

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