Archive for the 'comentario'

Lunes 17 / febrero / 2014

Effects of resistance training on central blood pressure and wave reflection in obese adults with prehypertension

Filed under: comentario — Mario Hernández Cueto — febrero 17th, 2014 — 9:09

Effects of resistance training on central blood pressure and wave reflection in obese adults with prehypertension

ComentadoPor: A.  Figueroa.  Journal of Human Hypertension (2014) 28, 143–144.

Young overweight and obese adults with prehypertension are at increased risk of developing hypertension1 and arterial stiffness (pulse wave velocity, PWV). Moreover, obesity is associated with increased aortic blood pressure (BP) and augmentation index (AIx), two independent predictors of cardiovascular events and all-cause mortality. The increase in aortic systolic BP (SBP) is in part attributed to an increased wave reflection from peripheral arteries to the aorta that causes augmentation of the second systolic peak (P2), leading to a subsequent increase in AIx.

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Martes 11 / febrero / 2014

Differences in vascular reactivity between pregnant women with chronic hypertension and preeclampsia

Filed under: comentario — Mario Hernández Cueto — febrero 11th, 2014 — 8:54

Differences in vascular reactivity between pregnant women with chronic hypertension and preeclampsia

ComentadoPor: Toshitaka Mori, Kazushi Watanabe, Ai Iwasaki, Chiharu Kimura, Hiroshi Matsushita, Koichi Shinohara y Akihiko Wakatsuki.  Hypertension Research (2014) 37, 145–150.


The purpose of this study was to evaluate the distinct pathogenic mechanisms underlying chronic hypertension in pregnancy and preeclampsia in terms of oxidative stress and vascular reactivity. A total of 17 women with uncomplicated pregnancies, 30 women with preeclampsia and 17 women with chronic hypertension were evaluated. We measured serum derivatives of reactive oxygen metabolites (d-ROMs; marker of oxygen free radicals), flow-mediated vasodilation (FMD; marker of endothelial function) and intima-media thickness in the carotid artery (IMT; marker of atherogenesis) during pregnancy and 1 month after delivery.

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Miércoles 5 / febrero / 2014

2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC-8)

Filed under: comentario — Mario Hernández Cueto — febrero 5th, 2014 — 13:18

2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC-8)

ComentadoPor: James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J et al.

JAMA. 2014;311(5):507-520. doi:10.1001/jama.2013.284427.

Hypertension is the most common condition seen in primary care and leads to myocardial infarction, stroke, renal failure, and death if not detected early and treated appropriately. Patients want to be assured that blood pressure (BP) treatment will reduce their disease burden, while clinicians want guidance on hypertension management using the best scientific evidence. This report takes a rigorous, evidence-based approach to recommend treatment thresholds, goals, and medications in the management of hypertension in adults. Evidence was drawn from randomized controlled trials, which represent the gold standard for determining efficacy and effectiveness. Evidence quality and recommendations were graded based on their effect on important outcomes.

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Jueves 16 / enero / 2014

Sex and Age Differences in the Relation of Depressive Symptoms With Blood Pressure

Filed under: comentario — Mario Hernández Cueto — enero 16th, 2014 — 8:02

Sex and Age Differences in the Relation of Depressive Symptoms With Blood Pressure

ComentadoPor: Mauli T. Shah, Alan B. Zonderman y Shari R. Waldstein.  American Journal of Hypertension, Volume 26, Issue 12, Pp. 1413-1420.

Longitudinal associations between depressive symptoms and blood pressure have been inconsistent. Most studies have examined incident hypertension as an outcome, and few have examined effect modification.
Depression and depressive symptoms are established risk factors for cardiovascular disease (CVD),1 but the mechanisms underlying this relation are unclear. Hypertension may be a mechanism through which depressive symptoms influence CVD pathogenesis. Prior literature has identified inconsistent longitudinal associations between depressive symptoms and blood pressure (BP).
Results demonstrate sex and age differences in the relation between depressive symptoms and blood pressure. Findings suggest the potential importance of preventing, detecting, and lowering depressive symptoms to prevent hypertension among women and older adults.

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