Archive for the 'comentario'

Jueves 28 / agosto / 2014

Association of Urinary Sodium and Potassium Excretion with Blood Pressure

Filed under: comentario — Mario Hernández Cueto — agosto 28th, 2014 — 11:19

Association of Urinary Sodium and Potassium Excretion with Blood Pressure

ComentadoPor: Andrew Mente, Ph.D., Martin J. O’Donnell, M.B., Ph.D., Sumathy Rangarajan, M.Sc., Matthew J. McQueen, M.B., B.Ch., Paul Poirier, M.D., Ph.D., Andreas Wielgosz, M.D., Ph.D., Howard Morrison, Ph.D., Wei Li, Ph.D., Xingyu Wang, Ph.D., Chen Di, B.Sc., Prem Mony, M.D., Anitha Devanath, M.D., Annika Rosengren, M.D., Aytekin Oguz, M.D., Katarzyna Zatonska, M.D., Ph.D., Afzal Hussein Yusufali, M.D., P N, Et Al.  Engl J Med 2014; 371:601-611August 14, 2014DOI: 10.1056/NEJMoa1311989.

Hypertension affects 1 billion people and is considered to be a leading cause of death, stroke, myocardial infarction, congestive heart failure, and chronic renal impairment.1-4 Sodium intake is reported to be a modifiable determinant of hypertension.5,6 The International Study of Salt and Blood Pressure (INTERSALT),7 but not another large study,8 showed a modest association between higher levels of sodium intake and higher blood pressure. However, INTERSALT was not large enough to determine whether the association varied according to region, participant characteristics, or levels of sodium or potassium intake.

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Miércoles 30 / julio / 2014

La Hipertensión Arterial y DOCTUS VIII. Algunas consideraciones

Filed under: comentario — Mario Hernández Cueto — julio 30th, 2014 — 10:15

La Hipertensión Arterial y DOCTUS VIII. Algunas consideraciones

Por: Ing. Lisandra Nuñez Aguilar.   Revista Cubana de Cardiologia y Cirugía Cardiosvascular , Vol. 20, No. 1 (2014).

ComentadoLa hipertensión arterial HTA es una de las enfermedades que afecta más frecuentemente a la población adulta en el mundo. Numerosos estudios han demostrado que esta afección está presente en el 20 al 30 % de las personas mayores de 15 años.   Estudios realizados en Cuba han evidenciado una alta prevalencia de las enfermedades cardiovasculares, entre ellas, la HTA, estimándose que afecta a una tercera parte de la población adulta. En los últimos años, su incidencia y sus complicaciones cardiovasculares están aumentando notablemente, sobre todo por el progresivo envejecimiento de la población y el paulatino incremento de la esperanza de vida.

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Lunes 2 / junio / 2014

Yet Another Study Reports Poor Control of Elevated Blood Pressure

Filed under: comentario — Mario Hernández Cueto — junio 2nd, 2014 — 8:31

Yet Another Study Reports Poor Control of Elevated Blood Pressure

ComentadoPor: Lewis H. Kuller.  American Journal of Hypertension Volume 27, Issue 6, Pp. 773-774.

The article by Sorlie et al. (this issue) provides estimates of the prevalence of hypertension and of awareness, treatment, and control among the Hispanic community. Previous publications from this study have described the study design and recruitment and baseline measurements and the distribution of risk factors and prevalent cardiovascular disease. The reports documented very substantial variability in the prevalence of hypertension by specific Hispanic groups and communities.

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Jueves 29 / mayo / 2014

Telmisartan activates endogenous peroxisome proliferator-activated receptor-d and may have anti-fibrotic effects in human mesangial cells

Filed under: comentario — Mario Hernández Cueto — mayo 29th, 2014 — 8:32

Telmisartan activates endogenous peroxisome proliferator-activated receptor-d and may have anti-fibrotic effects in human mesangial cells

ComentadoPor: Daisuke Mikami, Hideki Kimura, Kazuko Kamiyama, Kunio Torii, Kenji Kasuno, Naoki Takahashi, Haruyoshi Yoshida y Masayuki Iwano.   Hypertension Research (2014) 37, 422–431.

Telmisartan, an angiotensin II receptor type 1 blocker (ARB), was recently reported to promote lipolysis in mice by acting as a peroxisome proliferator-activated receptor (PPAR)-d activator, although in clinical studies, it has also been recognized to activate PPAR-? as a major cause of its pleiotropic actions. The aim of this study was to investigate whether telmisartan activates endogenous PPAR-d and thereby exerts anti-fibrotic effects in human mesangial cells (HMC).

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