Prevalence of white-coat and masked hypertension in national and international registries

Por: Manuel Gorostidi, Ernest Vinyoles, José R Banegas y Alejandro de la Sierra.  Hypertension Research (2015) 38, 1–7.

In the past two decades, techniques for the measurement of blood pressure outside the medical setting have unmasked highly prevalent situations. A significant proportion of patients with office blood pressure levels above the thresholds for diagnosing hypertension or above the limits where those being treated are considered to be adequately controlled actually show normal ambulatory blood pressure levels.

Combination therapy of hypertension in the elderly: a subgroup analysis of the Combination of OLMesartan and a calcium channel blocker or diuretic in Japanese elderly hypertensive patients trial

Por: Toshio Ogihara, Takao Saruta, Hiromi Rakugi, Ikuo Saito, Kazuaki Shimamoto, Hiroaki Matsuoka, Satoshi Teramukai, Jitsuo Higaki, Sadayoshi Ito y Kazuyuki Shimada for the COLM investigators.   Hypertension Research (2015) 38, 89–96.

Combination of OLMesartan and a calcium channel blocker or a diuretic in Japanese elderly hypertensive patients (COLM) trial demonstrated that olmesartan combinations with a CCB or diuretic have similar effects on reducing cardiovascular risk in elderly hypertensive patients. However, the safety profiles suggest that olmesartan combined with CCB may be preferable to olmesartan combined with diuretic. In this subgroup analysis, we further evaluated the effects and safety of these combinations in elderly (65–74 years old (y.o.)) and very elderly (75–84 y.o.) hypertensive patients.

Hypertension management initiative prospective cohort study: comparison between immediate and delayed intervention groups.

Por: S W Tobe, M Moy Lum-Kwong, S Von Sychowski, K Kandukur, A Kiss y V Flintoft.  Journal of Human Hypertension (2014) 28, 44–50

The Heart and Stroke Foundation of Ontario’s Hypertension Management Initiative (HMI) was a pragmatic implementation of clinical practice guidelines for hypertension management in primary care clinics. The HMI was a prospective delayed phase cohort study of 11 sites enrolling patients in two blocks starting 9 months apart in 2007. The intervention was an evidence-informed chronic disease management program consisting of an interprofessional educational intervention with practice tools to implement the Canadian Hypertension Education Program’s clinical practice guidelines.