Tag Archive 'Queloides'

Viernes 16 / marzo / 2012

The emerging role of antineoplastic agents in the treatment of keloids and hypertrophic scars: a review.

Filed under: Temas de meses anteriores — Dr. Pável Reyes Rodríguez — marzo 16th, 2012 — 1:23 PM

The emerging role of antineoplastic agents in the treatment of keloids and hypertrophic scars: a review
Shridharani SM, Magarakis M, Manson PN, Singh NK, Basdag B, Rosson GD.
Ann Plast Surg. 2010 Mar;64(3):355-61.

ovidwebcgi2The management of keloids and hypertrophic scars continues to challenge health-care providers. Though both forms of pathologic scarring are distinct entities at the macro and microscopic level, their etiologies and treatment are often similar. Potential treatment approaches are progressing, and combinations of treatment options have been proposed in the literature with promising outcomes. The treatment evolution has reached a level where molecular therapeutic modalities are being investigated. Currently, no gold standard treatment exists. Overall success rates and patient satisfaction seem to be slowly climbing, but additional investigational studies must continue to be performed. Several studies have investigated antineoplastic agents, and there seems to be a marked improvement in rates of recurrence, patient satisfaction, and overall quality of scar when these agents are used. Intralesional injection and/or wound irrigation with interferon-a2b, interferon-g, mitomycin-C, bleomycin, or 5-fluorouracil seems to have a positive effect on the reduction of pathologic scars. There is mounting evidence that these drugs used alone or in combination therapy, have the potential to be an integral part of the treatment paradigm for hypertrophic scars and keloids.

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Viernes 16 / marzo / 2012

Antimitotic drug injections and radiotherapy: a review of the effectiveness of treatment for hypertrophic scars and keloids.

Filed under: Temas de meses anteriores — Dr. Pável Reyes Rodríguez — marzo 16th, 2012 — 1:14 PM

Antimitotic drug injections and radiotherapy: a review of the effectiveness of treatment for hypertrophic scars and keloids
Wang XQ, Liu YK, Wang ZY, Wei Jun, Jiang YZ, Qing Chun, Lu SL.
Int J Low Extrem Wounds. 2008 Sep;7(3):151-9.

col2-3-coverScars are a common complication of surgery or burn wound management. Scars occur over the body, affecting people of both sexes and all ages. Scar therapy is a constant clinical challenge; antimitotic drugs and radiotherapy are used with varying degrees of success. This article examines the success of both these types of treatment modalities.
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Viernes 16 / marzo / 2012

Management of keloids and hypertrophic scars.

Filed under: Temas de meses anteriores — Dr. Pável Reyes Rodríguez — marzo 16th, 2012 — 12:48 PM

Management of keloids and hypertrophic scars
Juckett G, Hartman-Adams H.
Am Fam Physician. 2009 Aug 1;80(3):253-60.

genericpar0001imageKeloids and hypertrophic scars represent an exuberant healing response that poses a challenge for physicians. Patients at high risk of keloids are usually younger than 30 years and have darker skin. Sternal skin, shoulders and upper arms, earlobes, and cheeks are most susceptible to developing keloids and hypertrophic scars. High-risk trauma includes burns, ear piercing, and any factor that prolongs wound healing. Keloid formation often can be prevented if anticipated with immediate silicone elastomer sheeting, taping to reduce skin tension, or corticosteroid injections. Despite the popularity of over-the-counter herb-based creams, the evidence for their use is mixed, and there is little evidence that vitamin E is helpful.

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